CANDLE syndrome: an extended clinical spectrum
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چکیده
منابع مشابه
P02-009 - Candle syndrome: expanding spectrum
Introduction CANDLE syndrome is an exceptional inflammatory condition starting within the first months of life, and comprising elevated fever, panniculitis with lipoatrophy, purplish and swollen eyelids, arthralgia, and developmental retardation. Most patients carry homozygous mutations in the PSMB8 gene that impair the assembly of the immunoproteasome (iP) and lead to interferon g deregulation...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 2014
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/keu298